POSSIBLE ROLE OF COVID-19 IN THE RELAPSE OF KLEIN-LEVIN SYNDROME

Possible role of COVID-19 in the relapse of Klein-Levin Syndrome

Klein-Levin Syndrome (KLS) is an extremely rare neurological disorder which can manifest as recurring spells of sleepiness, cognitive disturbances and behavioral changes.We present a novel case of KLS relapse in the setting of Coronavirus disease-19 (COVID-19).A 36-year-old Testosterone Support male who had a known history of KLS since adolescence

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A modified Delphi approach to develop a trial protocol for antibiotic de-escalation in patients with suspected sepsis

Abstract Background: Early administration of antibiotics in sepsis is associated with improved patient outcomes, but safe and generalizable approaches to de-escalate or discontinue antibiotics after suspected sepsis events are unknown.Methods: We used a modified Delphi approach to identify safety criteria for an opt-out protocol to guide de-escalat

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The Role of Eryptosis in the Pathogenesis of Renal Anemia: Insights From Basic Research and Mathematical Modeling

Red blood cells (RBC) are the most abundant cells in the blood.Despite powerful defense systems against chemical and mechanical stressors, their life span is limited to about 120 days in healthy humans and further shortened in patients with kidney failure.Changes in the cell membrane potential and cation permeability trigger a cascade of events tha

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